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RMD Open 3 , e000442

Developing potential therapies that can be administered less frequently could benefit societies as well as individual patients, and it is a clear focus area for Novo Nordisk, commented Brian Vandahl, Senior Vice President of Global Research Technologies at Novo Nordisk

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The DPP-4 inhibitors, which are oral antidiabetic drugs of a specific class, have now become one of the main therapeutic categories for T2D

Studies have found that high NNMT expression promotes the release of inflammatory factors in adipose tissue, and NNMTi can effectively alleviate adipose inflammation and improve the microenvironment by inhibiting NNMT